| Pair Name | Oxidized tea polyphenol, Sildenafil | ||
| Phytochemical Name | Oxidized tea polyphenol (PubChem CID: / ) | ||
| Anticancer drug Name | Sildenafil (PubChem CID: 135398744 ) | ||
| Structure of Phytochemical |
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| Structure of Anticancer Drug |
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| Pair Name | Oxidized tea polyphenol, Sildenafil | |||
| Disease Info | [ICD-11: 2C60] | Breast cancer | Investigative | |
| Biological Phenomena | Induction-->Blockade of cell cycle in Sub-G1 phase | |||
| In Vitro Model | MCF-7 | Invasive breast carcinoma of no special type | Homo sapiens (Human) | CVCL_0031 |
| MDA-MB-231 | Breast adenocarcinoma | Homo sapiens (Human) | CVCL_0062 | |
| Result | Sildenafil, in combination with flavonoids, may be considered a novel strategy for cancer treatment. | |||
| No. | Title | Href |
|---|---|---|
| 1 | Exploring the Synergistic Effect of Sildenafil and Green Tea Polyphenols on Breast Cancer Stem Cell-like Cells and their Parental Cells: A Potential Novel Therapeutic Approach. Anticancer Agents Med Chem. 2023 Nov 10. doi: 10.2174/0118715206276925231107060329. | Click |
